New to this edition: New chapter on palliative medicine. Five times the number of margin clinical photos. New echocardiography images. Double the number of dermatological images; including all the major lesion morphologies covered in a single page. 16 new authors. New sections on protein synthesis energy production and stem cells. New members of the International Advisory Board from India South Africa Poland and the Middle East. 7 new chapters from the International Advisory Board. Animated practical procedures including lumbar puncture central venous and bladder catheterization arterial cannulation etc.